Conformational Studies on Germancranolide Sesquiterpene Lactones - Cnicin From Centaurea maculosa-
Pullen, Kyle Thomas
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Sesquiterpene lactones, most commonly found in species of the plant family Compositae, are members of the terpenoid family and are one of the largest classes of naturally occurring organic compounds. The number of presently known, naturally occurring sesquiterpene lactones has grown to well over 1500 and is steadily rising. Sesquiterpene lactones have recently become of great interest to scientists after being claimed to have antidiabetic and antibiotic activity. In addition they have been proven to be insecticides, vermifuges, fish poisons, bacteriostatics, antifungals, analgesics, hypotonics and expectorants. Also, many plants belonging to the family Compositae which have a bitter taste due to presence of sesquiterpene lactones have been reported in folklore medicine to possess antibiotic activity.