The Diebold Symposium is an annual scientific meeting sponsored by the Biology Department of Kalamazoo College and is dedicated to the memory of Dr. Frances “Dieb” Diebold (1900-1989), a member of the Kalamazoo College Biology Department for 44 years.
Senior biology majors present the results of their Senior Integrated Projects (SIPS, formerly known as Senior Individualized Projects) at the Diebold Symposium. Presentations are made as short seminars or as posters, and the entire symposium is open to the public.
Abstracts are generally available to the public, but PDF files are available only to current Kalamazoo College students, faculty, and staff. If you are not a current K College student, faculty, or staff member, email us at email@example.com to request access to this material.
The Diebold Symposium was not held in 2011 and 2020.
Biological Framework: Previous study suggests promoters are key to gene regulation, can be regulated from far away. Mice strains C57BL/6 (BLK6) and DBA/2J (DBA) have differential gene expression in fear and anxiety genes. Experiments to isolate these differences, however, are laborious time-consuming.
Computational Framework: Hi-C data and single-cell data modalities all describe differential expression in slightly different ways. Data collected using Hi-C bulk and single-cell sequencing.
Goals: Simultaneous visualization of all modalities. Classifier for future gene assessment.
This project was a continuation of prior work done studying the local Kalamazoo Riverview Eastside site (KRE), which currently stands as a brownfield site. Soil sampling and testing, vegetation surveying, and bioindicator surveillance had already been conducted giving insight into on-site conditions leading to this, one of hopefully several more steps that may lead to the restoration of this site via phytoremediation.
Goals: Gain an understanding of heavy metal uptake within KRE vegetation. Find potential phytoremediators to
help generate phytoremediation-centered cleanup strategies for the site.
Working with experienced bird banders and handling birds has broadened my understanding of ecology, conservation and advocacy. My experience at both banding sites has revealed major frustrations with government funding. Currently, bird banders all around the U.S have seen significant limitations in volunteer work and educational opportunities. My literature review portion explored the key milestones that led to the unification and standardization of the bird banding process. There remains concerning trends of bird injury, stress, illness and mortality. Aspects of uncertainty extends to data connectivity and technological monitoring and driving home our responsibility over human disturbances to bird habitats and survival. Various developments and destruction of bird banding sites threaten the progress of bird bandings’ success and usefulness as a process to conservation and research.
The objective of this shadowing experience was to gain an understanding of the day-to-day operations of an orthodontic practice, including patient-receptionist etiquette, the use of topsOrtho software, and the roles of different staff members. I was able to observe and participate in various tasks such as booking appointments, updating patient charts, and learning about specific instrumentation and treatment plans. I gained valuable insights into the various aspects of operating an orthodontic practice successfully and was inspired by the results of treatments and patient interactions.
(Kalamazoo, Mich. : Kalamazoo College, 2023) Phillips, Mary
The purpose of this research is to better understand and investigate the five different drug bound states of the Hepatitis B Virus (HBV) and how they relate to the two differing strains. The intended outcome for the research project is to further the development of preventing infection of Hepatitis B through improved knowledge of virus classification and enhancing current antiviral drugs. Hepatitis B was chosen to research due to its icosahedral symmetry and unique behavior. Oftentimes the capsid protein (cp) is analyzed rather than the full capsid due to its identical behavior and increased simplicity. The HBV cp is 183 amino acids long, but is truncated at amino acid 149 and mutated to have a cysteine as its 150th amino acid along with replacing the other native cysteines with alanines to help with stability.