Browsing by Author "Lahti, Robert A."

An In vivo Study of the Role of Opiates in Schizoprenia. 3H-Spiroperidol Binding

Hosley, John (Kalamazoo College, 1981)

Since the 1950's, the development of antipsychotic drugs has lead to several physical models for schizophrenia. The preferred model is the Dopamine hypothesis, which relates schizophrenia to a malfunction of the ...

Isolation of Morphine-Like Factor from Brain and an Evaluation of its Pharmacological Properties

Kincaid, Vance L. II (Kalamazoo College, 1976)

Numerous researchers have found morphine and related opiates to interact with highly specific receptor sites which are present in greatest abundance in certain circumscribed areas of the brain, particularly in those ...

Receptor-Binding Studies of Agonists and Antagonists at the D2 Dopamine Receptor in Bovine Caudate

Francis, Jonathan W. (Kalamazoo College, 1984)

Antipsychotic drugs are thought to produce their therapeutic effects in schizophrenia by blocking receptors for the neurotransmitter dopamine in the brain. Several lines of evidence previously indicated, however, that ...