Browsing by Author "Jackson, Philip"
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Suramin Selectively Inhibits Inducible Nitric Oxide Synthase at the Calmodulin Binding Site
Jackson, Philip (Kalamazoo, Mich. : Kalamazoo College, 2012)Excessive amounts of the free radical nitric oxide (∙NO) can be cytotoxic and has been linked to neurodegenerative pathways involved in several diseases, including Alzheimer’s and Parkinson’s disease. Inhibition of nitric ... -
Suramin Selectively Inhibits Inducible Nitric Oxide Synthase at the Calmodulin Binding Site
Jackson, Philip (Kalamazoo College, 2011)Excess nitric oxide (-NO), synthesized from L-arginine by nitric oxide synthase (NOS), has been linked to a number of pathological conditions. Inhibition of NOS is, therefore, currently a target for drug design. NOS requires ... -
Suramin Selectivity Inhibits Inducible Nitric Oxide Synthase at the Calmodulin Binding Site
Jackson, Philip (Kalamazoo College, 2011)Excess nitric oxide (NO), synthesized from L-arginine by nitric oxide synthase (NOS), has been linked to a number of pathological conditions. Inhibition of NOS is, therefore, currently a target for drug design. NOS ...