Browsing by Author "D'Alecy, Louis G."

Development and Characterization of the Rat Paraplegia Model

Neal, Sandra (Kalamazoo College, 1986)

Paralysis in the lower extremities following trauma, extrinsic compression, profound shock, and certain surgical procedures in the human is an important problem. In the past, research has been restricted to a rabbit ...

The Effects of Storage and Ageing of Human Blood on the Levels of Asymmetric Dimethylarginine, and an Analysis of its Protein Source in Erythrocytes

Gudipati, Swapna (2013)

Nitric oxide (NO) is a vasodilator produced from arginine via the enzyme nitric oxide synthase (NOS). An endogenous inhibitor of NOS is asymmetric dimethylarginine (ADMA). ADMA is a protein metabolite that is produced ...

Opioid Dependent Reductions in Selected Ambient Temperature Following Acute, Intermittent Hypoxia

Carney, Karen (Kalamazoo College, 1993)

Exposure to non-lethal acute hypoxia (hypoxic conditioning - HC) increases tolerance to subsequent hypoxia in mice. Naloxone reverses this increase in tolerance, and attenuates a decrease in body temperature (Tb). ...

Paraplegia Model in the Rat: Glucose Exacerbation of Neurological Deficit

Neal, Susan (Kalamazoo College, 1986)

Spinal cord damage due to ischemia is a serious, underappreciated and relatively refractory problem in clinical practice. Mechanical and pharmacologic means of protecting the spinal cord from ischemic damage are relatively ...

SNC80: The Metabolic Role of a Nonpeptidic-ligand as a Highly Selective Delta-l Opioid Agonist

Pai, Deepa (Kalamazoo College, 1997)

Hypoxic conditioning (HC), severe intermittent hypoxia, results in an increased hypoxic tolerance. Previous studies have shown HC to be dependent upon a central opioid pathway and have been strongly associated with a ...