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DSpace Repository
DSpace is a digital service that collects, preserves, and distributes digital material. Repositories are important tools for preserving an organization's legacy; they facilitate digital preservation and scholarly communication.
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LRRK2 G2019S Missense Mutation Increases PKA Activity in a Preliminary Investigation
(Kalamazoo College, 2018)Mutations in leucine-rich repeat kinase 2 genes (LRRK2) are the most common genetic causes of Parkinson's disease (PD); they are also associated with some sporadic cases of PD. Despite the relevance ofLRRK2 in PD, its ... -
Using Proximity and Behavioral Analysis of Fallow Deer {Dama dama) to Detect Possible Sources of Environmental Enrichment
(Kalamazoo College, 2017)With the development of environmental enrichment (EE) in zoos, a variety of approaches have become popularized throughout the world, as they have been seen to decrease stereotypical and often harmful behaviors while ... -
The Effect of Climate Change on Mosquito Vector and Arbovirus Dynamics in Distinct Locations of South America, Africa, and Asia
(Kalamazoo College, 2018)There are numerous mosquito vectors of pathogens on every continent except for Antarctica. All of these vectors and pathogens exhibit temperature dependent life cycles. Studies have shown that as temperatures rise the ... -
Using Arduino-Based Microclimate Sensors To Uncover Niche or Neutral Tendencies Of an Endangered Dune Thistle
(Kalamazoo College, 2018)Pitcher's thistle (Cirsium pitcheri) is an imperiled monocarpic thistle endemic to the dunes of the Great Lakes region. Traditional approaches for researching endangered plant species are generally in three styled: ... -
Streptococcus mitis Downregulates Pseudomonas aeruginosa Quorum Sensing and Virulence Expression in Pairwise Interaction Model
(Kalamazoo College, 2017)Cystic fibrosis (CF) is a respiratory genetic disorder that increases lung susceptibility to infection. Most CF lung infections contain Pseudomonas aeruginosa and Streptococcus mitis bacteria, which are drug resistant ... -
Northern Madtom (Noturus stigmosus) Use of Artificial Reefs in the St. Clair-Detroit River System
(Kalamazoo College, 2017)Once shipping channels were created on the St. Clair-Detroit River System, fish populations and their habitat diminished, leading to beneficial use impairments in the system. Six artificial reefs were constructed to restore ... -
Biophysical and structural characterization ofBTB domain proteins Kaiso and Mizl
(Kalamazoo College, 2018)The central role deregulated protein-protein interactions (PPIs) play in human disease make PPIs important targets for drug discovery efforts. PPI interfaces have historically been difficult to disrupt using drug-mediated ... -
DNA Barcoding of 16S and COI Genes Provides Preliminary Evidence for Cryptic Nemertean Species near Bocas del Toro, Panama
(Kalamazoo College, 2018)Cryptic species are morphologically indistinguishable species only identified as separate species via DNA barcoding. Because of the high likelihood of species misidentification, cryptic species pose a serious challenge to ... -
Distribution and Dominance Patterns of Invasive Species at the Albion College Whitehouse Nature Center
(Kalamazoo College, 2018)Invasive species cause devastating economic and ecological damage every year. Many hypotheses help explain aspects of invasive plant biology such as means of invasion or factors that can make a community susceptible to ... -
Investigation of Kinase/s to Determine the Catalytic Activity of SGKl at a Site Regulated by Drugs of Abuse
(Kalamazoo College, 2018)Drug addiction is a serious health issue with limited and inadequate treatment options. Although dysregulation of the brain reward circuitry has been implicated in addiction, our understanding of signaling changes within ... -
The Effects of Constant and Fluctuating Thermal Environments on Life History Traits of the Fathead Minnow, Pimephales promelas
(Kalamazoo College, 2018)Climate change can impact the life history of organisms through elevating temperatures And the increasing intensity of daily fluctuations. Most experiments addressing the effects of climate change do so with constant ... -
Comparing Mean Alveolar Concentration, Heart Rate, and Recovery Time in Canines when Anesthetically Induced via Alfaxalone or Propofol
(Kalamazoo College, 2018)This study compares a relatively newly released drug, alfaxalone, and an older, reliable drug that many veterinarians trust, propofol. The data collected is compared to determine if one drug is more effective than the ... -
Impact of Arthropod Presence on Monarch Butterfly Oviposition
(Kalamazoo College, 2017)Wild monarch butterflies {Danaus plexippus) are becoming more of a rare sight to see in most areas of North America where they used to be plentiful (Stenoien et al., 2016). Advancements in farming methods, urban expansion ... -
Culvert Inventories and Their Ecological Impacts in Van Buren County, MI
(Kalamazoo College, 2017)In the continental U.S. a vast abundance of road-stream crossing sites can be found passing under any road, often without the awareness of the public. Road-stream crossing sites such as culverts and bridges impact the ... -
A Study of the Efficacy of Curcumin Based Drugs for the Treatment of Glioblastoma
(Kalamazoo College, 2017)Glioblastoma is the most aggressive and common form of brain cancer in adults. Those diagnosed often only have a few months to live. However, recent studies have uncovered a promising, new option for treatment: curcumin. ... -
Synergistic Effects of FGF-2 and BMP-7 in Bone Regeneration for Alveolar Clefts
(Kalamazoo College, 2018)Cleft palate is the most common congenital craniofacial birth defect and occurs by the improper fusion of the palatal shelves during the sixth week of gestation. Among cleft palate patients, 75% also present with alveolar ... -
T1R2 and T1R3 Knockouts in a Mouse Model Showed Significant Attenuation of Fuctose-Induced, Salt-Sensitive Hypertension
(Kalamazoo College, 2017)The increasing amount of fructose used in the Western diet and increased fructose consumption result in metabolic syndrome, obesity, and hypertension. The specific cellular mechanisms leading to these ailments are highly ... -
The Correlation Between Obesity and Aortic Stenosis in Patients Who Underwent Surgical Intervention
(Kalamazoo College, 2017)Scientists and physicians are always looking for ways to improve the health of patients, especially when it comes to people's lifestyles. Obesity has become an increasingly prevalent metabolic disorder in the US over time; ... -
Computational Assessment of X-ray Digital Subtraction Angiography to Assess Balloon Test Occlusion in Watershed Stroke Risk Patients
(Kalamazoo College, 2018)Balloon Test Occlusion (BTO) is an elective, preoperative procedure to assess brain perfusion and function during an occlusion of the internal carotid artery (ICA). This allows physicians to determine if the patient can ... -
Letter from C.B. Williams to President Stetson
(1923-08-27)Professor C.B. Williams writes to retired Kalamazoo College president Herbert Lee Stetson about travel conditions on the S.S. President Lincoln. He focuses on the typhoon they sailed through but also mentions other travelers ...
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